Validating a Local Arterial Input Function Method for Improved Perfusion Quantification in Stroke
نویسندگان
چکیده
منابع مشابه
Defining a local arterial input function for perfusion MRI using independent component analysis.
Quantification of cerebral blood flow (CBF) using dynamic-susceptibility contrast MRI relies on the deconvolution of the arterial input function (AIF), which is commonly estimated from the signal changes in a major artery. However, it has been shown that the presence of bolus delay/dispersion between the artery and the tissue of interest can be a significant source of error. These effects could...
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BACKGROUND AND PURPOSE The choice of arterial input function (AIF) can have a profound effect on the blood flow maps generated on perfusion-weighted MR imaging (PWI). Automation of this process could substantially reduce operator dependency, increase consistency, and accelerate PWI analysis. We created an automated AIF identification program (auto-AIF) and validated its performance against conv...
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Background Modern MRI myocardial perfusion protocols use rapid venous bolus injections, typically 3-5 ml/s of 5-15 ml of agent over a few seconds. The resulting arterial input functions are rapidly varying with high agent concentrations (Fig. 1A and 1B) and thus typically require high temporal resolution acquisitions (~1 sec), custom pulse sequences and complex processing methods for perfusion ...
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Different software tools for quantification of myocardial perfusion SPECT (MPS) studies are routinely used. Several perfusion parameters can be computed automatically. Interpretation of the MPS should start with visual inspection of the rotating planar images, visual analysis of reconstructed SPECT slices and then quantitative analysis to confirm the visual impression. Quantification should be...
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Elias Kellner, Irina Mader, Daniel Nico Splitthoff, Marco Reisert, Katharina Förster, Thao Nguyen-Thanh, Peter Gall, and Valerij G. Kiselev Department of Radiology, Medical Physics, University Medical Center Freiburg, D-79106 Freiburg, Germany, Section of Neuroradiology, Neurocenter of the Freiburg University Hospital, D-79106 Freiburg, Germany, Department of Cardiovascular Surgery, Albert-Ludw...
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ژورنال
عنوان ژورنال: Journal of Cerebral Blood Flow & Metabolism
سال: 2011
ISSN: 0271-678X,1559-7016
DOI: 10.1038/jcbfm.2011.78